Duonase Nasal Spray - 140 mcg + 50 mcg

This drug has a generic name Azelastine HCl Fluticasone Propionate BP, which is a nasal spray for the treatment of Asthma and allergies. It works by lowering the effect of natural chemical histamine in the body. Presence of histamine in the body can lead to symptoms like itching, sneezing, watery eyes, and runny nose.

Azelastine HCl Fluticasone nasal spray helps in preventing the above symptoms and other kind of nasal allergies. It is also prescribed for relieving the symptoms of asthma. It is sold under various trade names including Dymista, Duonase (made by Cipla) among several other brands. This medication is used for other conditions which are not listed here.

Important information about Azelastine HCl, Fluticasone Propionate BP

Don’t take this medicine if you are allergic to Azelastine HCl Fluticasone Propionate. Inform your doctor if you regularly use other medicines that persuade drowsiness like cold or allergy drugs, narcotic pain killers, sedatives, sleeping pills, muscle relaxers, seizures, depression, or anxiety.  They can increase your sleepiness. Taking alcohol while taking Azelastine HCl, Fluticasone Propionate BP medication may increase the likelihood of some side effects.

Before using Azelastine HCl, Fluticasone Propionate BP

Before using this medicine, remember to discuss all the above mentioned points with your doctor. In order to ensure whether this medicine is safe for you, tell your doctor about whole medical history. If you are pregnant or planning to become pregnant, ask your doctor about safe usage of this medicine. In case of breast feeding, ask your doctor if you can use Azelastine HCl, Fluticasone Propionate BP medication without affecting your baby because it may pass into breast milk. This medication is not recommended for children under 5 years of age.  

Dosage information

You should use Azelastine HCl, Fluticasone Propionate strictly by following the instructions given by your doctor. Do not alter the dosage unless your doctor advices you to do so. Prohibit the use of this drug if the prescription period is over. All medicines are come with a patient leaflet; you should go through the leaflet to know detailed information.  Here are the steps which you should follow while using it-

§  Fix the pump on the bottle.

§  Prepare the pump by priming it (removing air by spraying) 3-4 times in air, away from your body until you get a fine mist.

§  Prime the pump if you haven’t used the medicine for a while, say 3 days in a continuous manner.

§  When the pump is ready, slowly start blowing your nose to clear it of any mucus or blockage.

§  After that insert the medication bottle nozzle into your nostril; make sure to point it directly up into the nose.

§  Close the other nostril with your finger and remain in a straight posture. Then pump the spray and inhale slowly in a continuous manner.

§  Spray the appropriate amount of medicine as directed by your doctor.

§  Clean the nozzle properly after use. Don’t sneeze or blow your nose just after using the medication.

Inform your doctor if your condition might deteriorate after using this medicine regularly. Always store this medicine in a cool and dry place, far away from the reach of heat, moisture, pets and children.

What if you miss a dose

If you miss a dose, take the drug as soon as possible. Don’t use the medicine if the next dose time is close. Do not double up the dose in order to compensate the missed one.

What if you overdose

In case of overdose, get emergency medical help or call your doctor immediately. Overdose of this drug may result into high degree of sleepiness.

Things to avoid

Azelastine HCl, Fluticasone Propionate BP medication (Dymista, Duonase) may impact on your thinking ability and reflexes. So, don’t involve in the activities that require attention and alertness like driving, etc.

Side effects

Azelastine HCl, Fluticasone Propionate BP may/ may not cause side effects in you. Some of the common allergic reactions caused by this

medicine are hives, breathing difficulty, swelling on tongue, face, lips, or throat. Seek medical emergency in case you experience any of the above listed symptoms. Some rare side effects caused by this medicine are bronchospasm (breath shortness, chest tightness, wheezing), or irregular heartbeat. While, less serious side effects are changed taste, especially bitterness, headache, giddiness, dry mouth, sore throat, unusual weight gain, bleeding in nose, redness in eye, nausea, cough, or runny nose. These are not only the ones; there may be some other side effects.

Interaction with other drugs

Before using Azelastine HCl, Fluticasone Propionate BP spray (Dymista, Duonase), inform your doctor about present medications which you may be using such as cimetidine (Tagamet) as they may interact with this nasal spray medication and affect the normal functionality.  Other drugs which may cause effect on the functioning of this medicine are cold and other allergy medications, narcotic pain killers, sleeping pills, depression or anxiety medications, muscle relaxers, or medicines for seizures. They can increase sleepiness induced by Azelastine HCl, Fluticasone Propionate BP spray.

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